Diamine Oxidase from Cultured Roots of Hyoscyamus niger
نویسندگان
چکیده
منابع مشابه
Two Tropinone Reductases with Distinct Stereospecificities from Cultured Roots of Hyoscyamus niger.
Tropinone is an alkamine intermediate at the branch point of biosynthetic pathways leading to various tropane alkaloids. Two stereospecifically distinct NADPH-dependent oxidoreductases, TR-I and TR-II, which, respectively, reduce tropinone to 3alpha-hydroxytropane (tropine) and 3beta-hydroxytropane (psi-tropine), were detected mainly in the root of tropane alkaloid-producing plants but not in n...
متن کاملcDNA encoding tropinone reductase-II from Hyoscyamus niger.
Two stereospecific NADPH-dependent reductases, TR-I and TR-11, constitute a branching point in the biosynthesis of tropane alkaloids. TR-I catalyzes the stereospecific reduction of tropinone to tropine (Koelen and Gross, 1982), whereas TR-I1 reduces tropinone to pseudotropine (Drager et al., 1988). We previously characterized TRs that had been purified from cultured roots of Hyoscyamus niger (H...
متن کاملEffects of Arginine Pretreatments on Oxidative Stress Damages and Alkaloid Content in Roots of Hyoscyamus niger under Nickel Stress
Heavy metal pollution is a worldwide problem with serious environmental consequences. The objective of the present experiment was to investigate whether arginine as nitric oxide precursor and or polyamines substrate can decrease the destructive effects of oxidative stress induced by nickel contamination in Hyoscyamus niger plant. In this study the effects of arginine pretreatment on alkaloid co...
متن کاملStructures and expression patterns of two tropinone reductase genes from Hyoscyamus niger.
In the biosynthesis of tropane alkaloids, two tropinone reductases (TRs) catalyze reduction of tropinone to different stereoisomers, tropine and pseudotropine. Two TRs from Hyoscyamus niger have 64% of identical amino acids and hence a common evolutionary origin. In this study, genomic clones of TRs were isolated from H. niger. Their sequence comparison showed that although they have the same e...
متن کاملDiamine oxidase and cadaverine metabolism.
We have recently presented evidence that diamine oxidase is rcsponsiblc for a portion of the metabolism of histamine in several species (1, 2). This evidence is largely based on the alteration of histamine metabolism produced by compounds which are known to inhibit diamine oxidase in vitro. The inhibitors used were isonicotinylhydrazine (3) and aminoguanidine. The latter is reported to be the m...
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ژورنال
عنوان ژورنال: Plant Physiology
سال: 1990
ISSN: 0032-0889,1532-2548
DOI: 10.1104/pp.93.1.216